Mark, given your comments, I made some changes:
-- I relocated and slightly reduced the size of the upper loop so it doesn't stick out into the walkway.
-- I moved the blue tracks so they are 4.5" from the purple tracks.
-- I then moved the green yard and removed 1 spur so it's 36" from the wall and 4.5" from the passing siding. With the purple track on an incline, you might be able to reach that track. If necessary, another spur can be removed from the yard. Only you know how far you can reach and if you're willing to use a stool if needed.
-- I fixed the elevation of the new spurs in the lower right. As a result of adding those, the grade for the purple track went up to 2.7%.
-- I changed those spurs slightly and added an O42 setup as an alternative. The way the #4 was configured, there wasn't enough room on the upper spur to hold a full car, so I removed the 6.2" straight. There wasn't any room to put something between the spurs anyway, so they might as well be close together to give you more room above them (where the O42 setup is).
-- I also exploded the room boarders a bit so the baseboard for the actual layout is more visible.
I have to say I hadn't planned on this being a viable design, I was just trying to show the space. However, I really like the extended run from loop-to-loop with both a town and a yard in between. I can also envision pulling a train counterclockwise through the upper loop through the tunnel, backing some empties onto the holding track, picking up the full cars from the mine, moving the empties to the mine and then heading back to town.
Anyway, see what you think.