When you're starting from a blank slate as you are, enjoy the fabulous array of choices that are out there today! It's a brave new world of sorts when it comes to lighting. I'll echo what Chris said above re: black ceilings. Mine are white. But if I had to do things over again, I'd go with black ceilings. If you're using acoustic tiles (i.e., suspended ceilings), black is usually a slight up-charge over the more common white options.
As for lighting, I would go two routes: high-hats (or recessed lights) for "basic" room lighting, and track lighting for directing the light to specific areas of the layout.
There are TONS of options today that simply didn't even exist yesterday. If budget is not as big a concern for you, take a look at the Philips HUE "smart LED" system. I chose this route, and couldn't have timed my purchases better in that Best Buy and Home Depot had HUGE sales on these lights just this past Black Friday / Cyber Monday weekend. Philips must have been having a special promotion, so the stores passed the great pricing along to consumers. Lights that were normally $50/each could be purchased for $30/each. Still not chump change, but a very timely discount nonetheless, since I was planning to purchase close to 3 dozen lights. I purchased the BR30 HUE lights for my train room's high-hats and some of the track lighting as well. The BR30 lights fit perfectly into room's recessed lighting as well as into PAR38 track-lighting units. These serve both the basic room lighting needs, as well as broad directed flood lights on the train layout. I also purchased PAR16 HUE lights that serve as narrower spotlights for those areas of the train layout that I wanted to highlight specifically.
Now here's the kicker with a smart-system such as Philips HUE: the lights can be programmed to change color (and intensity level) with your iPhone or iPad with readily available apps (i.e., from Philips as well as independent 3rd parties). The effects are impressive, and I can't wait to try this all out on my new layout in a couple of weeks. In particular, I plan to use white lights for daylight running, then switch to blue/violet lights to simulate night-time running... all with the same light units. No need to purchase different color lights, because EACH light can produce an array of colors. If you go with a system such as Philips HUE, be sure to get the latest "third generation" bulbs wherever possible, as they have more vivid color capabilities.
When it comes to track lighting, don't skimp on the quantity -- nor the quality. As you will find out, good lighting is EVERYTHING. I went with Lightolier track AND track-light head-units. Lightolier has 3 track systems: two "older" style systems -- a "one circuit" track called Basic, and a "two-circuit" track called Advent. More recently, their third system was introduced and is a much "lower profile" design called Radius. The latter system being newer is slightly less expensive than the earlier systems, and the various special components like L's, T-s, ceiling clips (for suspended ceilings), and power-routing connectors are more readily available.
For the actual lighting head-units, I also went with Lightolier because the same units can be used on all three of their track systems. I had the older 2-circuit track installed years ago on the dry wall soffits of our finished basement. And when I chose to add additional lighting a few weeks ago directly on the suspended ceiling tiles, I chose the newer, low-profile Radius track and had it installed directly along the grids of the suspended ceiling. You hardly can see the new track it blends in so well. And the Lightolier head-units work on either track systems, which is an added bonus.
The world is your oyster in terms of head-unit styles. So I recommend going with a "complete system" rather than just buying one-off, Home Depot knock-off track lights. The Lightolier lights I chose actually can be purchased in two or more pieces: a head-unit that goes directly into the track, and then a shade attachment that can be one of several styles (cone, bezel, ring, etc...). Additionally, accessories are available for each light head that allow for special light modification. Many of my lights have hex cell louvers (or grids) over the light, so as to direct the light better AND reduce the glare of the lights when viewing them from the side. When you have an around-the-perimeter-of-the-room layout design, this is less of an issue... since the lights will typically be directed toward the walls and/or train layout AWAY from your eyes. However, when you have a walk-around, island layout in the middle of the room, you'll be walking around the layout and some of the lighting may be in the view of your eyes at times -- which can be a rather bright distraction depending on the height of your ceiling and your viewing angle to certain scenes of the layout. THAT's where the grids/louvers come in VERY handy. Trust me on this... they've made a HUGE difference, so I've employed them extensively with my lighting configuration. So if these kinds of subtleties are important to you, go with a "system" that accommodates these light modifiers and allows easy configuration of light shade attachments.
Oh yes... one last word about the lights themselves. Plan your purchases and light-switch controls carefully. With incandescent and halogen lights, dimmers were fairly commonplace. And compatibility was much less an issue. With LED's, it's an entirely different story. My train room has 4 light circuits -- controlled by Decora-style switches in a 4-gang box. One of these is a Lutron dimmer that controls the one circuit of track lights that I chose to keep as the older halogen style, which lights up the walls of the room (including a colorful custom backdrop as well as train shelves). The other three switches are simple on/off switches for the other 3 light circuits in the room. Standard dimmers don't work with these smart LED lights. Instead, these lights are dimmed through a special unit called the Philips Hub, which is actually a WiFi-based hub (connected to your whole-house WiFi router) that allows individual lights and groups of lights to be controlled/dimmed with your iPhone or iPad (or even voice-activated by Alexa and other similar technologies). I'm not big on the voice-activated stuff... just isn't my cup of tea. But I'm very impressed with what can be done using the iPhone/iPad to change light levels and colors in the room. I've only just begun experimenting with this technology, but it's got great potential to run "scripts" that automatically run timed daytime-to-nightime sequences (and vice versa).
As I said earlier, the technology treadmill is moving at lightning speed here. And much of this "smart home" stuff is VERY new, and only in its infancy -- or perhaps didn't even exist -- as recently as 5 years ago. So have fun getting up to speed on these new technologies. Don't rush into things. Look at what's right for you. And make your choices accordingly. It'll be a big investment for sure. Hope this helps!!!
Good lighting can make a WORLD of difference, and bring your enjoyment level of the trains and your layout's scenery to new heights that need to be experienced rather than just talked about in words.