Jerry
You are planning a good sized layout and need to tell us at least roughly what your track plan will be,what kind of trains and how many you think you will be running and type of locomotives. That will be a clue to the potential railpower load in amps or watts as well as the number of power districts needed.
For example a lighted passenger train with one or more engines is a much higher load than a freight train with engine and lighted caboose. In designing the wire runs and the type and size of transformers, the type of powered track switches, the railpower load in amps as represented by the number of engines and lighted cars is the determining factor for wire size and transformer capacity..
Lets assume, for example, you plan on a dual mainline and a sizable freight or service Yard and will be running in Conventional control with possibility of adding Command control later. Lets define that as 3 power districts: two mains and the yard. A suggested railpower bus of #12 would consist of a Common wire and perhaps 3 #12 Hot wires, one for each mainline loop and one for the yard. The Common would serve all districts as the "Layout Common" whereas each Hot would serve a single separate district.
This is a simple explanation of railpower needs without consideration for a lower voltage[ below 18VAC] for motorized accessory power or lighting Bus. Also if not powered by railpower a bus wire run[s]or home run wiring for track switch motors will be needed.
Terminal strips are useful for power distribution from Bus to rails. The photo below shows a "Hub and Spoke" T-strip which was one of three used to distribute railpower on a 15x 23/8x12 layout with three power districts. You can see the white, red, black and green #12 wire runs of the Bus connected at the bottom of the strip and from the same terminal screws similar wires outbound to the next Hub. The white is the Layout Common and the colored are the Hot wires for the three districts. Then, you can see pairs of #16, a white Common and Colored Hot extended out, as pairs, for soldering to rail flanges.[at one point this system was successfully modified to operate TMCC and DCS]
I have to leave now for some "honey dos" but hopefully this will not be too confusing and will trigger some layout planning before running wires. Others will likely help you out also.
Second photo on another layout shows rough wiring before cover up of a "bus" for railpower[red, black white], home run wires for Tortoise switch motors[blue, yellow], power wires for accessories[green] and lighting[brown] wire runs.