Is that a Scale Big Boy or a traditional one?
I now have one of each and the Scale one Requires O-72 MINIMUM.
I'm pretty sure that goes for all makes of the Scale version.
The Imperial Railking one will run on insanely tight curves (O-31) but looks very odd doing so. It also has 4" overhang to the outside on said tight curves (Why it looks wrong) Inside overhang is under 2" but best bet is to lay out a couple curves at your desired spacing and put the equipment on them. Move them back and forth and ensure a minimum of 1/4" gap exists, thains rock a bit when running so 1/4" may or may not be enough gap.
I prefer a minimum of O-48 for my Imperial Big boy and the new layout will have easements to O-72 at the tightest on the mainlines so I can run the Scale version.