I much prefer real names rather than funny ones, choosing to reference locations that have historical significance to the area (upstate NY, one of many areas with a rich RR background).
Buildings / areas I have on the layout include:
Highland Station (after Highland Park in Rochester NY)
Despatch Yards (after the old late 1800s / early 1900s Despatch Car Shops in what is now East Rochester, NY)
Goodman Street Yards (from the railroad yard near Goodman St and University Ave in Rochester, NY)
The Pole [my Ameritown barber shop building, complete with Miller Engineering barber pole (after a real barber shop of the same name currently operating in Penfield, NY)
Cobbs Hill (after a 100 or so acre park in Rochester NY, which just happens to be located a couple of good throws with a hardball from where I grew up as a kid)
Grandkids and visitors as well enjoy seeing the ties to the history of the area.