Looking at the older F style units,realize that operating these units with the rear facing forward would be possible,but awkward as can be.You would have a bad field of vision with an F style locomotive.
Now getting onto say the GP style of locomotive you have a better field of vision and can operate that locomotive fairly easy long hood,and even some railroads,Southern for example,had controls that faced long hood on the right side and the control stand was formatted to operate that way.It allowed railroads without the availability of a wye or turntable the option to have units facing which ever way.
Now on today's locomotives a lot of your trains say on the NS,that run from Chicago to Roanoke ,they most likely will never take the head end power off,and so it doesn't really matter other than the lead unit facing with the F end forward,how the other units in the consist are turned.They are just being used as needed power and dynamic braking.
Short hood forward is the desired way of operating on long haul trains.FRA really prefers this also.I'm not certain if they actually have a law out about it right now,but it has been a topic of debate to make it law.It's just safer when possible to operate with short hood forward.
But like on the road switcher job I work,it doesn't really matter because I'm usually switching in a yard or an industry,and really never travel more than 30 miles one way.I'm also usually on a SD40-2 or a GP-38,and the one GP-38 we've had lately has the controls on the right side facing long hood end.
One other situation that I can explain.Our 233 piggy back train has it's rear trailing units,set up for when they drop them off in Columbus,Ohio at the Rickenbacker intermodal facility,to be used on the 236 going back east,with the 233 rear unit facing short hood .So that consist is purposely built in that manner .