Wow! Thanks to everyone. So at least there is track there. Bloomsburg runs a "Polar Express" during the holidays from Bloomsburg to Danville. It's a short hop from there down to Northumberland and not too far in the other direction to Scranton.
laz57 - thanks for the link to trainorders. Some good stuff there but haven't looked at it in detail yet.
ChipR - the 1947 schedule seems to say there was service. It's about 120 miles from Harrisburg
to Scranton. I believe trains could average between 40-50 mph in the 40's so a non-stop trip should take about 3 hrs. The 6-1/2 hours seems to indicate many stops and/or a much slower average speed.
Tim - great input and ChipR ran with it to get the 1947 schedule.
coloradohirailer - it makes sense that one would think that there would be direct service between these two cities. I think that there was emphasis on Philadelphia as a hub and trains going northwest from there would have probably been associated with the Lehigh Valley and/or Reading. Philly to Harrisburg was probably PRR and/or Reading. I don't know what ran north from Harrisburg other than the NS that iaz57 mentioned.
Now that I've got some stuff to work with, I'll check this out in more detail. Again, thanks to everyone for their input.
Steve