Some people asked why I tried so hard to get perfect signal in every area of my layout. There were a few locos that seem more sensitive to signal problems. When the layout got perfected, all locos operate smoothly. There were two (out of 20 or so) that would start up when power was applied. They don't anymore. I didn't focus on the engine after struggling to make any difference. I looked at the layout as a whole. Now with adding many more engines, I have not had anymore issues like this.
That said, my TMCC base is only connected for testing their locos. It still is my biggest offender. I'm running two rail and it does seem to make a bigger difference. The base must be placed at the furthest point of the layout from the TIU (and my engine yard) per Carl T's advice of finding the sweet spot. There, it makes the least impact for my layout. Maybe it would make a difference in three rail??