"My train layout is in my garage (Houston) and it gets down to 50 degrees F."
"When I had my train layout in our big Garage in Slidell, LA, the heat and humidity were much more of a problem than the cold ever was, and we did get some cold nights."
I live in the Mobile area, and Houston, Slidell (N.O.) and Mobile all share the typical Gulf Coast weather, and my trains are in my 12X24 train building, that is neither cooled nor heated unless I'm using it. It is shaded and insulated, so it never gets extremely hot (sweltering), and my window A/C cools it down quickly. I do not use it every day.
Winter - it gets cold out there, and my space heater takes much longer to catch up than does my A/C. Low-20's weather does happen here (usually it's 35 - 45 - 50 at night), and it may well get in the upper 30's in there on those extreme nights. They are rare.
Never had any temperature-related problems. Some of that stuff has been out there 20 years. Humidity is apparently not an issue, either (a garage would be worse), and I live 20 miles from the Gulf and 5 blocks from Mobile Bay, so... But, again, it's a sealed building.