I use a Digitrax DCC system on my layout. I currently have an 8 Super Chief (old) command station and 2 8 Amp boosters. I don't need all that, I have run the lay out with just the command station and one 5 amp booster.
As for what system is most common in O scale, I think it depends on where you are and who you ask, If Digitrax is the predominent system in your area, HO, NO, and O scalers will be using it. If NCE is most common same goes. Around here, NCE is most common the the east and north side of the city, and Digitrax on the west and south sides. And there are some pockets of Lenz users and also EasyDCC (CVP Products). The best choice is something that other modelers in your area use, so you can get some help getting started.
Most newer O scale locos do not draw more than one amp. However, old USH and MG brass and teh diecast stuff from 30-40 years ago, tend to draw 2-3 amps under load. Getting a meter and testing the draw on a loco before you install a decoder can give you good information. that said a 5 amp system should be able to handle at least 2 and probably 3 newer locos simultaneously without any issues.
Remember with DCC, the signal is a standard, so ANY brand of decoder will work with any control system. Within the control system however, you need to use throttles and command stations from the same manufacturer.