Here is your pretty typical conventional issue - the train runs faster on one side of the layout vs. the other side. Sounds pretty common and a few power feeds usually does the trick.
I don't like to run my trains at Mach 2 - I like to actually look at them as they go by. I have a very simply 4x8. Two 0-31 loops and one 0-42 loop. I use MTH Z-1000 transformers for power and Lionel tubular track, two fees on each oval.
I see my Williams and Lionel engines, without cruise control, typically like to run faster on the far side, away from the control panel. Again, I have a feed on each loop on this side. Slower back by the transformers. Adding/subtracting power feeds doesn't make a difference and my table is level and I have confirmed this with a 4 foot spirit level so there is no elevation changes on the track.
Any suggestions? Obviously this is most easily seen at slow speeds (which I like to run). Cranking it up a bit masks it but is still somewhat noticeable.