I built my layout power with Hammond transformers capable of outputting 20A at 18 volts, and TPCs to vary the track voltage. That's the equivalent of PowerHouses plus Powermasters (which are current off-the-shelf products). Instant trip magnetic breakers limit each loop to a max of 10 amps and the transformer is fused for 20 amps. I two loops with a single 20A transformer and a TPC for each loop. The 10 amp magnetic breakers allow a short in a loop from tripping the upstream breakers in the TPC or transformer so each loop's operation does not affect the other loop.
My club uses a pair of Z4000s to power four power districts (3 loops + yard/programming tracks). Two districts are powered by each Z4000 and we rely on the Z4000's breaker for power protection. Unfortunately, when a short occurs on one of the Z4000's output channels shuts off all power output.
Operationally, the biggest problem with sharing a single power source (transformer) with multiple track districts (loops) is a short that trips the transformer's breaker will stop trains on other districts/loops. The same issue applies to sharing conventional operation from a single power source - the fwd-neutral-rev power interruption affects all locos using that source. In my club's show operations a club member causing a short in the yard stops operation on the main line powered by that Z4000. For a home layout, this may be acceptable.
So, the best practice is to power each loop with its own transformer and PowerMaster. For a home layout, you can manage with less gear. A single PowerHouse is sufficient for two or three trains and could power your whole layout. If the PowerHouse breaker is frequently tripping from overload, you'll have to add a second transformer. You can add a PowerMaster for each loop for conventional control on an individual loop, or run both loops from a single PowerMaster (I am assuming a single conventional loco is operating). If you want to control two conventional locos, you'll need two PowerMasters - one for each loop).
I haven't used one, but the ZW-L should provide the equivalent of four PowerMasters in a single device.