It's wireless ... the unexpected can happen.
The TMCC1 system used the same crystals for every handset so adjacent layouts interfered with one another unless some agreement is made assigning engine #s (or the crystals were swapped). Additionally, the TMCC signal can transfer passively to non-connected tracks so adjacent layouts share their signals.
DCS handheld to TIU is wireless and is subject to interference. We observed two sources at several shows: DCC operation on adjacent layouts (I guess the DCC handhelds use the same band), and the show venue's bright lights generate RF noise.
These days, 2.4Ghz is the handheld to base communication. Tablet/phone/PC apps connect using WiFi. The Legacy Base allows selection of 9 channels. Channel 1 is below WiFi channel 1, and channel 9 is above WiFi channel 11. I recommend you set the Legacy Base to channel 9 to avoid most interference.
Add the LCS WiFi and the MTH WIU into the mix and you have lots of opportunities to mess up the communications. At a show last December, we added a wireless router to provide a common access point for both the LCS WiFi and WIU. The router was a fire-breathing 802.11-alphabet model aimed at the high speed home gaming and streaming market. Before the show started, all systems tested OK and weak signal on Legacy CAB2s was attributed to low batteries. Once the show started, hundreds of guests with their cell phones hunting for WiFi came in and filled the 2.4Ghz band, train cams came alive on 2.4Ghz, etc. Legacy locos were uncontrollable. Fortunately, two of us had notebooks and tablets loaded with WiFi sniffers and network diagnostic tools so we were able to observe that the router (which combines adjacent WiFi channels for throughput) was dominating the 2.4Ghz spectrum. We didn't have a frequency analyzer but I suspect the router radiated lots of RF noise outside of designated channels because even Legacy channel 9 didn't work.
Once we removed the high performance router, Legacy and MTH systems worked fine and the CAB2s had signal 50 ft. away. An older router (no high performance channel bonding) was substituted and tested OK. Conclusion: the high performance router was actively jamming the Legacy base and other 2.4Ghz communications.
Another observation is when a custom wireless configuration such as we tried is installed on a club layout, you need a network engineer with passwords and familiarity with all the networked devices on hand to troubleshoot the system. And, as soon as something doesn't work, the operators start pulling cables to get their control system working. We have enough issues with "engine not found" and don't need spooky WiFi to deal with at show time.
Lessons learned ... your home layout and pre-opening hours at shows are not the same RF environment as a public show. Set WiFi channels on your devices to avoid interference but otherwise leave the WiFi devices in their default configurations. Have a fallback control strategy. KISS.