Sorry I have not responded sooner, been tied up and such.
Yes, the sound works fine in conventional. There are some aspects you can't control as to options, people talking and such I think, but I've never bothered to even check it out. A legacy loco with chuff or rumble in conventional just as well as in digital control.
TMCC locos don't run that well in convetnional, many of the jackrabbit a bit and I avoid them. Recent Legacy locos run very well in coventional, better than conventional locos, they seem to have some programming built into them that makes them respnd to the conventional throttle well.
Also, note that cruise works in conventional if you turn on the Odyssey switch. You can even turn it on and off in conventional, although it is a bit cumbersome to do.
I don't run my Legacy locos with WBB, particulary because of the speed differences cited above, but also because I prefer to run locos with sound. If you are talking about a WBB diesel and you wire the tow motors in series, the loco will run a lot closer to the same speed as the Legacy diesels, but still not quite the same. If the difference is not that great when you leave them free, it probably won't hurt to hook them up - I'd do it if they were mine.