Here is what you have to work with. Special bottle neck board and ribbon board to the front for the Sound Power board. Not a lot of room above these board once the diecast hood assembly is installed. The original Dallee to TMCC conversions require a new frame for more room. 8 ohm Speaker is in the fuel tank. A wafer speaker, very small, you would also have to change here, I believe MTH speakers are 16 ohm.
Antenna location was an issue, improved on later installs. MTH units don't require an antenna, not an issue. Head/Rear lights and cab light voltages may have to be changed. Power pick-up from track should be fine.
Another look. Note the the single motor double flywheel assembly to the two drive towers takes a good bit of space. Full cab detail doesn't allow much to the rear.