"So my only real concern is the ability of the front trucks to navigate a curve without striking the fixed pilot."
The above issue is largely non-existent, as any decent model's parts and pieces will not create such a situation. Now, attempting to run a non-swinging coupler on small curves is just almost always a lesson in frustration. It's all just physics and geometry. You can't change either.
As Jonathan said above: "Find yourself a cheap 2R dummy, lay some track and push it around."
Yep - get some stuff do some testing and design.
FYI - I just installed a fixed pilot on my Atlas NYC F2 - and it was a problem using the factory parts and instructions. So, be patient. (I had to shorten the actual coupler pocket a wee bit - the truck would not swing at all - see how the pocket jams up against the truck?; problem solved later with a bit of cutting.)
Done. That's an 072 curve; I still use the large hi-rail couplers in general, but my sclae steamers have scale couplers on the front, and this F2 is not a switcher, and I dislike swinging pilots, so... The car is there just for the photo.