Got a little curious after some discussion in the ES44 pilots thread, and had a closer look at a few of my engines.
Here is the ES44, which I also posted in that thread. Definitely integral to the truck casting and not removable:
Here is the SD45, also not removable:
But, here is an Alco S2. Removable!
Very cool!
So maybe it is the four wheel vs. six wheel trucks, or maybe it just varies from model to model. Still, it's great that they are headed in that direction, at least with some locos.