An option that can work in cases where you have a lot of wheels and weight is to just eliminate them.
I recently ran a 24+test reported elsewhere using a five to six year old Railking loco I had not run in 19 months. Prior to the test, the only problem I had setting it up and checking it out is that it kept throwing its traction tires - from the first minute I ran it after 19 months, it threw all its tires - one after another, sometimes two at a time, and again every time I would position them back on (none broke, they just came off). I finally just removed all four. It made no difference in how it ran or pulled. It subsequently pulled ten hopper cars (three of them very heavy cast metal ones) and a caboose around my layout for over a day without any slippage or problems, including once a loop up a long (18 foot) 3 percent slope.
Frankly I was surprised, but it could not have worked any better with tires than that. Of course, it is a heavy loco and it had 12 other powered drivers, so its not your average situation . . .