My earliest memories of trains go back to playing with my Dad's HO railroad, which was designed very similar to the "Great South Pass" articles in "Model Railroader" way back in the mid 1950s. Very early memories include playing with his Tenshodo GN and CB&Q GP20s and SD9, and Varney NW2 switcher.
With the exception of Lionel trains from about age 6 thru 16 (sold them all to buy HO brass steam), and an 11 year sideline into three rail from 2003 thru 2014, I've never left HO. I'm still liquidating my 3 rail O collection, and plowing the money back into the basement HO railroad.
If you take your time laying your track properly, use metal wheelsets (which you check with an NMRA gauge to make sure the are properly gauged), and properly set your coupler height, and weight your cars properly, HO will run every bit as good as any three rail O model railroad. Granted, my three rail O scale experiences were 95% associated with a modular railroad, but I had far MORE derailment problems with three rail O than I ever had with HO. My most recent locomotive purchases were two HO Atlas ALCo S2 switchers, with ESU loc-sound. Runs better than any three rail O scale locomotive I've ever owned, as it does not have that jackrabbit 0 to 1 smph start that plagues every darn TMCC locomotive I owned (and MTH DCS locomotive when I could get them to run).
My advice, is find a local HO club that allows younger members, or consider joining a modular HO group that sets up at train shows. Buy yourself the equipment necessary to model what you like, say a couple of CSX AC4400s, and a string of coal cars, with at FRED on the end. Make sure that club runs DCC, and buy the locomotives with DCC installed sound. There is a LOT of GREAT RUNNING HO, with awesome SOUND out there.
Then make your decision. Based on where your interests lie, your best served modeling in HO.
The HO world is your oyster.
Regards,
GNNPNUT